RNA Editing Generates a Diverse Array of Transcripts Encoding Squid Kv2 K+ Channels with Altered Functional Properties
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RNA Editing Generates a Diverse Array of Transcripts Encoding Squid Kv2 K+ Channels with Altered Functional Properties
We have cloned a Kv2 potassium channel from squid optic lobe termed sqKv2. Multiple overlapping sqKv2 cDNA clones differed from one another at specific positions by purine transitions. To test whether the purine transitions were generated by RNA editing, we compared a 360 nucleotide genomic sequence with corresponding cDNA sequences (encoding S4-S6) isolated from individual animals and lying on...
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ژورنال
عنوان ژورنال: Neuron
سال: 1997
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(00)80383-9